Small Molecule Sensors Targeting the Bacterial Cell Wall
نویسندگان
چکیده
منابع مشابه
Effect of a small molecule Lipid II binder on bacterial cell wall stress
We have recently identified small molecule compounds that act as binders of Lipid II, an essential precursor of bacterial cell wall biosynthesis. Lipid II comprised a hydrophilic head group that includes a peptidoglycan subunit composed of N-acetylglucosamine (GlcNAc) and N-acetylmuramic acid (MurNAc) coupled to a short pentapeptide moiety. This headgroup is coupled to a long bactoprenol chain ...
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ژورنال
عنوان ژورنال: ACS Infectious Diseases
سال: 2020
ISSN: 2373-8227,2373-8227
DOI: 10.1021/acsinfecdis.9b00515